This Buddha statue is made in the city of Patan in Nepal which is known for the quality of the work of its craftsmen.
It is made of brass then covered with a partition of stones (turquoise, coral and lapiz-lazuli) which  are glued by hand to give a beautiful appearance to the statues.
 
Signification
Dharmachakra mudra: attitude of setting in motion the Wheel of the teaching of the Law of Dharma